Advancing Intracellular Target Discovery with Constrained Peptide Screening Platforms

• Explore how intracellular constrained peptide libraries and diverse cross-linking modalities can expand access to challenging intracellular targets beyond the reach of conventional therapeutic approaches.
• Compare different peptide screening strategies and the trade-offs involved in selecting for affinity, stability, cellular permeability and functional biological activity.
• Discover how functional peptide selection in living cells can identify modulators of transcription factors and other complex intracellular protein-protein interactions, creating new opportunities for therapeutic development.

Speakers:

Jody Mason

Chief Scientific Officer, Revolver Therapeutics & Professor of Biochemistry

University of Bath