Advancing Macrocyclic Peptide Libraries for Intracellular Drug Discovery

9:30 am - Wednesday 2nd December 2026

  • Understand the relationship between molecular weight, polar surface and membrane permeability to enable accessing intracellular targets and formulation-free approaches to oral delivery.
  • Library synthesis and screening methods for de novo generating membranepermeable cyclic peptides to targets of choice.
  • Gain insights into selecting the right macrocycle format for protein-protein interaction targets.

Speakers:

Associate Professor
EPFL